Indicators on phenobarbital sodium obat apa You Should Know

Indicators on phenobarbital sodium obat apa You Should Know

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Drug interactions: Most studies of clinically important drug interactions transpiring with the barbiturates have concerned phenobarbital.

pentobarbital will lessen the level or effect of conjugated estrogens by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

Animal info. Phenobarbital sodium is carcinogenic in mice and rats just after lifetime administration. In mice, it produced benign and malignant liver mobile tumors. In rats, benign liver cell tumors were being noticed quite late in life.

pentobarbital will reduce the level or effect of lumacaftor/ivacaftor by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.

pentobarbital will decrease the level or effect of buprenorphine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.

pentobarbital will lower the extent or effect of ritonavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an get more info eye on.

pentobarbital will reduce the level or effect of glecaprevir/pibrentasvir by affecting hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will minimize the extent or effect of pimozide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unidentified.

pentobarbital will decrease the extent or effect of diclofenac by affecting hepatic enzyme CYP2C9/ten metabolism. Minimal/Importance Not known.

pentobarbital will lower the extent or effect of trazodone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.

pentobarbital will reduce the extent or effect of celecoxib by affecting hepatic enzyme CYP2C9/10 metabolism. Minor/Importance Unknown.

fentanyl intranasal and pentobarbital both improve sedation. Keep away from or Use Alternate Drug. Limit use to patients for whom alternative cure choices are insufficient

pentobarbital will decrease the level or effect of bosentan by influencing hepatic enzyme CYP2C9/ten metabolism. Minor/Significance Unknown.

pentobarbital will minimize the extent or effect of eucalyptus by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Mysterious.